3-Pyrrolidinemethanol, (3R)-
(R)-Pyrrolidin-3-ylmethanol
CAS: 110013-18-8
Molecular Formula: C5H11NO
3-Pyrrolidinemethanol, (3R)- - Names and Identifiers
| Name | (R)-Pyrrolidin-3-ylmethanol |
| Synonyms | D-beta-Prolinol (R)-3-Pyrrolidinemethanol (3R)-3-Pyrrolidinemethanol (R)-Pyrrolidin-3-ylmethanol (r)-pyrrolidin-3-ylmethanol 3-Pyrrolidinemethanol, (3R)- (3R)-pyrrolidin-3-ylmethanol (3R)-pyrrolidin-3-ylMethanol (R)-3-Pyrrolidin-3-yl-methanol |
| CAS | 110013-18-8 |
| InChI | InChI=1/C5H11NO/c7-4-5-1-2-6-3-5/h5-7H,1-4H2/t5-/m1/s1 |
3-Pyrrolidinemethanol, (3R)- - Physico-chemical Properties
| Molecular Formula | C5H11NO |
| Molar Mass | 101.15 |
| Density | 0.978 |
| Boling Point | 176 °C |
| Flash Point | 90 °C |
| Water Solubility | Slightly soluble in water. |
| Vapor Presure | 0.339mmHg at 25°C |
| pKa | 14.93±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Sensitive | Hygroscopic |
| Refractive Index | 1.454 |
3-Pyrrolidinemethanol, (3R)- - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37 - Wear suitable gloves. S60 - This material and its container must be disposed of as hazardous waste. |
| TSCA | No |
3-Pyrrolidinemethanol, (3R)- - Introduction
(R)-Pyrrolidine-3-methanol is an organic compound with the chemical formula C5H9NO and the structural formula CH3C(OH)(C4H4NH).
Properties:(R)-pyrrolidine-3-methanol is a colorless liquid with a special smell at room temperature. It is soluble in water and many organic solvents. It has a density of about 0.96g/cm³ and a boiling point of about 168°C.
Purpose:(R)-Pyrrolidine-3-methanol is an important chiral reagent, which plays an important role in enantioselective synthesis. It can be used to synthesize organic compounds such as chiral drugs, pesticides and spices. In addition, it can also be used in the preparation of catalysts and intermediates in organic synthesis.
preparation method:(R)-pyrrolidine -3-methanol preparation method is more, the commonly used method is obtained by the reaction of pyrrolidine and dimethyl sulfide. The synthesis of (R)-pyrrolidine-3-methanol requires attention to enantioselectivity, and chiral auxiliaries or catalysts are usually used to control the reaction.
Safety information:(R)-pyrrolidine-3-methanol is irritating to the skin and eyes, and should be rinsed with plenty of water immediately after contact. Pay attention to protective measures during operation, such as wearing protective gloves, glasses and protective clothing. Reactions with oxidants and acids should be avoided during storage and use.
Properties:(R)-pyrrolidine-3-methanol is a colorless liquid with a special smell at room temperature. It is soluble in water and many organic solvents. It has a density of about 0.96g/cm³ and a boiling point of about 168°C.
Purpose:(R)-Pyrrolidine-3-methanol is an important chiral reagent, which plays an important role in enantioselective synthesis. It can be used to synthesize organic compounds such as chiral drugs, pesticides and spices. In addition, it can also be used in the preparation of catalysts and intermediates in organic synthesis.
preparation method:(R)-pyrrolidine -3-methanol preparation method is more, the commonly used method is obtained by the reaction of pyrrolidine and dimethyl sulfide. The synthesis of (R)-pyrrolidine-3-methanol requires attention to enantioselectivity, and chiral auxiliaries or catalysts are usually used to control the reaction.
Safety information:(R)-pyrrolidine-3-methanol is irritating to the skin and eyes, and should be rinsed with plenty of water immediately after contact. Pay attention to protective measures during operation, such as wearing protective gloves, glasses and protective clothing. Reactions with oxidants and acids should be avoided during storage and use.
Last Update：2024-04-09 20:52:54
